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Interstates with National Access

Interstates and roadways with low rates of congestion

One-day drive or less to major Midwestern and Southern cities

Three of the area’s four interstates reach U.S. coastlines

The St. Louis region boasts four interstates and a high-priority corridor that connects the area to locations in every direction, along with an interstate loop that provides easy travel around the city. This system of interstates also offers fluid connection to and from all of the bistate area’s warehouse and distribution parks and ports on both sides of the Mississippi River. The region’s major interstates reach cities and states across the country.


St. Louis, Tulsa, Oklahoma City


Chicago, St, Louis, Memphis, New Orleans


Missouri, Kentucky, West Virginia, Virginia


Denver, Kansas City, St. Louis, Indianapolis, Columbus, Baltimore

Interstate Loop

I-270 (Missouri/Illinois) & I-255 (Missouri/Illinois)

Avenue of the Saints

corridor connecting St. Louis to Minneapolis/St. Paul, comprised of US-61, Iowa 218, and I-35

The St. Louis region’s freeway system experiences significantly lower congestion than other similarly sized U.S. urban areas according to the Texas Transportation Institute. In fact, in 2016, the St. Louis MSA had the lowest Travel Time Index of the 25 largest U.S. metro areas.

Improving Our Connections

Infrastructure investment is a top priority for the St. Louis region. Thanks to exceptional regional leadership, we have demonstrated public and private success by funding and delivering critical projects. During Summer 2018, we experienced three consecutive months of funding announcements, which exceeded $400 million, starting with IDOT and MoDOT’s announcement of the $220 million I-270 Chain of Rocks Bridge replacement over the Mississippi River, and followed by June’s announcement of $18.7 million in funding from Illinois’ new Competitive Freight Program, and July’s announcement by Terminal Railroad Association of St. Louis (TRRA) that they would fund the $222 million Merchants Rail Bridge replacement over the Mississippi River. This is a nationally-significant project as the Merchants Bridge provides services to six Class I railroads and Amtrak. In Winter 2019, TRRA received a $21.5 million Consolidated Rail Infrastructure and Safety Improvement (CRISI) grant to help with the reconstruction of the bridge.

United States Drivetimes